Effect of carotid artery stenting on cognitive function in patients with carotid artery stenosis: preliminary results.

نویسندگان

  • A S Turk
  • I Chaudry
  • V M Haughton
  • B P Hermann
  • H A Rowley
  • K Pulfer
  • B Aagaard-Kienitz
  • D B Niemann
  • P A Turski
  • R L Levine
  • C M Strother
چکیده

BACKGROUND AND PURPOSE Stenosis of the carotid artery may be a cause of reduced cognitive performance that can be ameliorated with placement of a stent. The goal of this study was to measure cognitive performance and speed of psychomotor performance prospectively before and after carotid stent placement. MATERIALS AND METHODS Patients referred for stent placement for a unilateral carotid artery stenosis were enrolled in the study. Neuropsychologic testing was performed with a Mini-Mental State Examination, an extended mental status examination, a subjective cognitive status measure, and a psychomotor performance test for speed. The severity of the stenosis was measured on angiograms performed before stent placement. Three months after stent placement, CT angiograms were performed and the neuropsychologic testing was repeated. Differences in neuropsychologic test scores before and after stent placement were calculated and tested for significance with a Student t test. RESULTS Seventeen patients with a single unilateral carotid stenosis of more than 50% completed the study. Stenosis of the carotid artery averaged 80% before treatment and 18% after treatment. After stenting, the scores from the extended mental status examination improved significantly. The scores from the subjective cognitive status measure also improved. No significant change was noted in the scores from the Mini-Mental State Examination or in the speed of psychomotor performance. CONCLUSION Carotid stent placement in patients with a unilateral stenosis of the carotid artery resulted in significant improvement in cognitive test scores in this highly selected patient group. Further studies are needed to confirm these preliminary observations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ANGIOPLASTY AND STENTING OF CAROTID ARTERY STENOSIS WITH EMBOLIC PROTECTION DEVICES

Background: Carotid artery stenting (CAS) has recently been recommended as an alternative to carotid endarterectomy (CEA) by some clinicians. Objective: This study was designed to evaluate the success rate and in-hospital and 30-day adverse events in our first experiences in Iran for CAS with protection devices, to document our results and guide further use of CAS. Methods: From December 2...

متن کامل

Carotid angioplasty and stenting in a patient with high grade stenosis of Internal Carotid Artery associated with both vertebral arteries and contralateral carotid occlusion

Severe internal carotid artery (ICA) stenosis is a common cause of cerebrovascular accident (CVA) in middle-aged patients. Contralateral carotid occlusion (CCO) in patients with severe ICA stenosis is associated with high risk of CVA. Carotid endarterectomy (CEA) is associated with more complications in patients with CCO than those without CCO. In this study, we present the case of a 61-year-ol...

متن کامل

Candida patients in a Jorjani center in Shahid Mohammadi Hospital of carotid Doppler sonnograghy findings in coronary artery Bypas grafting Bandar Abbas

Introduction: Nowadays caotid Dopplers sonography is gold standard for carotid artery screening in coronary aetery bypass grafting (CABG) candidates. This study was carried out in an angioplasty center in southern seaport in Iran to assesss theprevalence of artery stenosis and correlation of the atherosclerosis risk factor with the rate of artery stensis, and nence to define the high risk group...

متن کامل

A Lumped Parameter Method to Calculate the Effect of Internal Carotid Artery Occlusion on Anterior Cerebral Artery Pressure Waveform

Background and Objective: Numerical modeling of biological structures would be very helpful tool to analyze hundreds of human body phenomena and also diseases diagnosis. One physiologic phenomenon is blood circulatory system and heart hemodynamic performance that can be simulated by utilizing lumped method. In this study, we can predict hemodynamic behavior of one artery of circulatory system (...

متن کامل

Prevalence of carotid arterial diseases in patients undergoing CABG operations

 Introduction: Prevalence of stroke following coronary artery bypass graft surgery (CABG) is % 2.1-5.2 and associated with high mortality. The purpose of this study was to investigate the prevalence of carotid artery disease in patients undergoing CABG surgery.  Methods: This cross-sectional study was performed in the years 2010-2011 on 192 patients who underwent open heart surgery (CABG) in...

متن کامل

بررسی 291 مورد سونوگرافی داپلر کاروتید در بیماران کاندید CABG

Introduction: Doppler ultrasonography (DUS) is the most preferable method for screening of carotid artery disease in patients undergoing CABG. The purpose of this study was to investigate the frequency of carotid artery disease and determine the relation between known risk factors of atherosclerosis and rate of carotid artery narrowing in order to identify high-risk groups among patients schedu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 29 2  شماره 

صفحات  -

تاریخ انتشار 2008